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MALDI-TOF-MS reveals differential N-linked plasma- and IgG-glycosylation profiles between mothers and their newborns

During pregnancy, the mother provides multiple nutrients and substances to the foetus, with maternal immunoglobulin G (IgG) being actively transported to the foetus. Newborns depend on maternal IgG for immune-protection in their first months. The glycosylation of IgG has been shown to influence its...

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Detalles Bibliográficos
Autores principales: Jansen, Bas C., Bondt, Albert, Reiding, Karli R., Scherjon, Sicco A., Vidarsson, Gestur, Wuhrer, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036037/
https://www.ncbi.nlm.nih.gov/pubmed/27666402
http://dx.doi.org/10.1038/srep34001