A suppressor locus for MODY3-diabetes

Maturity Onset Diabetes of the Young type 3 (MODY3), linked to mutations in the transcription factor HNF1A, is the most prevalent form of monogenic diabetes mellitus. HNF1alpha-deficiency leads to defective insulin secretion via a molecular mechanism that is still not completely understood. Moreover...

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Detalles Bibliográficos
Autores principales: Garcia-Gonzalez, Miguel A., Carette, Claire, Bagattin, Alessia, Chiral, Magali, Makinistoglu, Munevver Parla, Garbay, Serge, Prévost, Géraldine, Madaras, Cécile, Hérault, Yann, Leibovici, Michel, Pontoglio, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036084/
https://www.ncbi.nlm.nih.gov/pubmed/27667715
http://dx.doi.org/10.1038/srep33087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036084/
https://www.ncbi.nlm.nih.gov/pubmed/27667715
http://dx.doi.org/10.1038/srep33087

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