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A suppressor locus for MODY3-diabetes
Maturity Onset Diabetes of the Young type 3 (MODY3), linked to mutations in the transcription factor HNF1A, is the most prevalent form of monogenic diabetes mellitus. HNF1alpha-deficiency leads to defective insulin secretion via a molecular mechanism that is still not completely understood. Moreover...
Autores principales: | Garcia-Gonzalez, Miguel A., Carette, Claire, Bagattin, Alessia, Chiral, Magali, Makinistoglu, Munevver Parla, Garbay, Serge, Prévost, Géraldine, Madaras, Cécile, Hérault, Yann, Leibovici, Michel, Pontoglio, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036084/ https://www.ncbi.nlm.nih.gov/pubmed/27667715 http://dx.doi.org/10.1038/srep33087 |
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