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Pharmacological Tie2 activation in kidney transplantation

AIM: To investigate the therapeutic potential of vasculotide (VT) - a Tie2 activating therapeutic - in kidney transplantation. METHODS: We performed a murine MHC-mismatched renal transplant model (C57Bl/6 male into Balb/c female) with 60 min cold and 30 min warm ischemia time. 500 ng VT was administ...

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Detalles Bibliográficos
Autores principales: Thamm, Kristina, Njau, Florence, Van Slyke, Paul, Dumont, Daniel J, Park, Joon-Keun, Haller, Hermann, David, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036127/
https://www.ncbi.nlm.nih.gov/pubmed/27683636
http://dx.doi.org/10.5500/wjt.v6.i3.573