Computational understanding and experimental characterization of twice-as-smart quadruplex ligands as chemical sensors of bacterial nucleotide second messengers

A twice-as-smart ligand is a small molecule that experiences a structural switch upon interaction with its target (i.e., smart ligand) that concomitantly triggers its fluorescence (i.e., smart probe). Prototypes of twice-as-smart ligands were recently developed to track and label G-quadruplexes: the...

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Detalles Bibliográficos
Autores principales: Zhou, Jie, Roembke, Benjamin T., Paragi, Gabor, Laguerre, Aurélien, Sintim, Herman O., Fonseca Guerra, Célia, Monchaud, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036188/
https://www.ncbi.nlm.nih.gov/pubmed/27667717
http://dx.doi.org/10.1038/srep33888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036188/
https://www.ncbi.nlm.nih.gov/pubmed/27667717
http://dx.doi.org/10.1038/srep33888

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