Differential effects of α4β7 and GPR15 on homing of effector and regulatory T cells from patients with UC to the inflamed gut in vivo

OBJECTIVE: Gut homing of lymphocytes via adhesion molecules has recently emerged as new target for therapy in IBDs. We aimed to analyse the in vivo homing of effector (Teff) and regulatory (Treg) T cells to the inflamed gut via α4β7 and G protein receptor GPR15. DESIGN: We assessed the expression of...

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Detalles Bibliográficos
Autores principales: Fischer, Anika, Zundler, Sebastian, Atreya, Raja, Rath, Timo, Voskens, Caroline, Hirschmann, Simon, López-Posadas, Rocío, Watson, Alastair, Becker, Christoph, Schuler, Gerold, Neufert, Clemens, Atreya, Imke, Neurath, Markus F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Inflammatory Bowel Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036234/
https://www.ncbi.nlm.nih.gov/pubmed/26209553
http://dx.doi.org/10.1136/gutjnl-2015-310022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036234/
https://www.ncbi.nlm.nih.gov/pubmed/26209553
http://dx.doi.org/10.1136/gutjnl-2015-310022

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