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Abnormal thymic stromal lymphopoietin expression in the duodenal mucosa of patients with coeliac disease

OBJECTIVE: The short isoform of thymic stromal lymphopoietin (TSLP), a cytokine constitutively expressed by epithelial cells, is crucial in preserving immune tolerance in the gut. TSLP deficiency has been implicated in sustaining intestinal damage in Crohn's disease. We explored mucosal TSLP ex...

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Detalles Bibliográficos
Autores principales: Biancheri, Paolo, Di Sabatino, Antonio, Rescigno, Maria, Giuffrida, Paolo, Fornasa, Giulia, Tsilingiri, Katerina, Pender, Sylvia L F, Papadia, Cinzia, Wood, Eleanor, Pasini, Alessandra, Ubezio, Cristina, Vanoli, Alessandro, Forbes, Alastair, MacDonald, Thomas T, Corazza, Gino R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036244/
https://www.ncbi.nlm.nih.gov/pubmed/26342013
http://dx.doi.org/10.1136/gutjnl-2014-308876