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The VanRS Homologous Two-Component System VnlRS(Ab) of the Glycopeptide Producer Amycolatopsis balhimycina Activates Transcription of the vanHAX(Sc) Genes in Streptomyces coelicolor, but not in A. balhimycina

In enterococci and in Streptomyces coelicolor, a glycopeptide nonproducer, the glycopeptide resistance genes vanHAX are colocalized with vanRS. The two-component system (TCS) VanRS activates vanHAX transcription upon sensing the presence of glycopeptides. Amycolatopsis balhimycina, the producer of t...

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Detalles Bibliográficos
Autores principales: Kilian, Regina, Frasch, Hans-Joerg, Kulik, Andreas, Wohlleben, Wolfgang, Stegmann, Evi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036315/
https://www.ncbi.nlm.nih.gov/pubmed/27420548
http://dx.doi.org/10.1089/mdr.2016.0128