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Levofloxacin‐Induced QTc Prolongation Depends on the Time of Drug Administration

Understanding the factors influencing a drug's potential to prolong the QTc interval on an electrocardiogram is essential for the correct evaluation of its safety profile. To explore the effect of dosing time on drug‐induced QTc prolongation, a randomized, crossover, clinical trial was conducte...

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Detalles Bibliográficos
Autores principales: Kervezee, L, Gotta, V, Stevens, J, Birkhoff, W, Kamerling, IMC, Danhof, M, Meijer, JH, Burggraaf, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036421/
https://www.ncbi.nlm.nih.gov/pubmed/27479699
http://dx.doi.org/10.1002/psp4.12085