Population Pharmacokinetics and Pharmacodynamics of the Calcimimetic Etelcalcetide in Chronic Kidney Disease and Secondary Hyperparathyroidism Receiving Hemodialysis

Etelcalcetide is a novel calcimimetic in development for the treatment of secondary hyperparathyroidism (SHPT). A population pharmacokinetic/pharmacodynamic (PK/PD) model was developed relating etelcalcetide exposures to markers of efficacy (parathyroid hormone [PTH]) and safety (calcium) using data...

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Detalles Bibliográficos
Autores principales: Chen, P, Olsson Gisleskog, P, Perez‐Ruixo, JJ, Xiao, J, Wilkins, J, Narayanan, A, Gibbs, JP, Melhem, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036423/
https://www.ncbi.nlm.nih.gov/pubmed/27639083
http://dx.doi.org/10.1002/psp4.12106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036423/
https://www.ncbi.nlm.nih.gov/pubmed/27639083
http://dx.doi.org/10.1002/psp4.12106

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