Cystic fibrosis transmembrane conductance regulator modulators in cystic fibrosis: current perspectives

Mutations of the CFTR gene cause cystic fibrosis (CF), the most common recessive monogenic disease worldwide. These mutations alter the synthesis, processing, function, or half-life of CFTR, the main chloride channel expressed in the apical membrane of epithelial cells in the airway, intestine, panc...

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Detalles Bibliográficos
Autores principales: Schmidt, Béla Z, Haaf, Jérémy B, Leal, Teresinha, Noel, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036583/
https://www.ncbi.nlm.nih.gov/pubmed/27703398
http://dx.doi.org/10.2147/CPAA.S100759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036583/
https://www.ncbi.nlm.nih.gov/pubmed/27703398
http://dx.doi.org/10.2147/CPAA.S100759

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