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Cystic fibrosis transmembrane conductance regulator modulators in cystic fibrosis: current perspectives

Mutations of the CFTR gene cause cystic fibrosis (CF), the most common recessive monogenic disease worldwide. These mutations alter the synthesis, processing, function, or half-life of CFTR, the main chloride channel expressed in the apical membrane of epithelial cells in the airway, intestine, panc...

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Detalles Bibliográficos
Autores principales:	Schmidt, Béla Z, Haaf, Jérémy B, Leal, Teresinha, Noel, Sabrina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036583/ https://www.ncbi.nlm.nih.gov/pubmed/27703398 http://dx.doi.org/10.2147/CPAA.S100759

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