Bulgecin A as a β-lactam enhancer for carbapenem-resistant Pseudomonas aeruginosa and carbapenem-resistant Acinetobacter baumannii clinical isolates containing various resistance mechanisms

Genetic screening of Pseudomonas aeruginosa (PSDA) and Acinetobacter baumannii (ACB) reveals genes that confer increased susceptibility to β-lactams when disrupted, suggesting novel drug targets. One such target is lytic transglycosylase. Bulgecin A (BlgA) is a natural product of Pseudomonas mesoaci...

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Detalles Bibliográficos
Autores principales: Skalweit, Marion J, Li, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036594/
https://www.ncbi.nlm.nih.gov/pubmed/27703329
http://dx.doi.org/10.2147/DDDT.S110193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036594/
https://www.ncbi.nlm.nih.gov/pubmed/27703329
http://dx.doi.org/10.2147/DDDT.S110193

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