Stochastic emergence of multiple intermediates detected by single-molecule quasi-static mechanical unfolding of protein

Experimental probing of a protein-folding energy landscape can be challenging, and energy landscapes comprising multiple intermediates have not yet been defined. Here, we quasi-statically unfolded single molecules of staphylococcal nuclease by constant-rate mechanical stretching with a feedback posi...

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Detalles Bibliográficos
Autores principales: Fukagawa, Akihiro, Hiroshima, Michio, Sakane, Isao, Tokunaga, Makio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036639/
https://www.ncbi.nlm.nih.gov/pubmed/27857576
http://dx.doi.org/10.2142/biophysics.5.25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036639/
https://www.ncbi.nlm.nih.gov/pubmed/27857576
http://dx.doi.org/10.2142/biophysics.5.25

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