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The role of charged surface residues in the binding ability of small hubs in protein-protein interaction networks
Hubs are highly connected proteins in a protein-protein interaction network. Previous work has implicated disordered domains and high surface charge as the properties significant in the ability of hubs to bind multiple proteins. While conformational flexibility of disordered domains plays an importa...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society of Japan (BSJ)
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036656/ https://www.ncbi.nlm.nih.gov/pubmed/27857564 http://dx.doi.org/10.2142/biophysics.3.27 |