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Staurosporine induces lamellipodial widening in locomoting fish keratocytes by abolishing the gradient from radial extension of leading edge

Fish epidermal keratocytes locomote along surfaces without overall cell size or shape changes, as kinematically described by the graded radial extension (GRE) model. We found that the cell size increased during locomotion after the addition of a low dose of staurosporine or K-252a, broad-spectrum pr...

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Detalles Bibliográficos
Autores principales: Mizuno, Takafumi, Sekiguchi, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036771/
https://www.ncbi.nlm.nih.gov/pubmed/27857594
http://dx.doi.org/10.2142/biophysics.7.69