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Analysis of SOX2-Regulated Transcriptome in Glioma Stem Cells

INTRODUCTION: Glioblastoma is the most malignant brain tumor in adults and is associated with poor survival despite multimodal treatments. Glioma stem-like cells (GSCs) are cells functionally defined by their self-renewal potential and the ability to reconstitute the original tumor upon orthotopic i...

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Detalles Bibliográficos
Autores principales: Acanda de la Rocha, Arlet M., López-Bertoni, Hernando, Guruceaga, Elizabeth, González-Huarriz, Marisol, Martínez-Vélez, Naiara, Xipell, Enric, Fueyo, Juan, Gomez-Manzano, Candelaria, Alonso, Marta M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036841/
https://www.ncbi.nlm.nih.gov/pubmed/27669421
http://dx.doi.org/10.1371/journal.pone.0163155