TetraMabs: simultaneous targeting of four oncogenic receptor tyrosine kinases for tumor growth inhibition in heterogeneous tumor cell populations

Monoclonal antibody-based targeted tumor therapy has greatly improved treatment options for patients. Antibodies against oncogenic receptor tyrosine kinases (RTKs), especially the ErbB receptor family, are prominent examples. However, long-term efficacy of such antibodies is limited by resistance me...

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Detalles Bibliográficos
Autores principales: Castoldi, Raffaella, Schanzer, Jürgen, Panke, Christian, Jucknischke, Ute, Neubert, Natalie J., Croasdale, Rebecca, Scheuer, Werner, Auer, Johannes, Klein, Christian, Niederfellner, Gerhard, Kobold, Sebastian, Sustmann, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036864/
https://www.ncbi.nlm.nih.gov/pubmed/27578890
http://dx.doi.org/10.1093/protein/gzw037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036864/
https://www.ncbi.nlm.nih.gov/pubmed/27578890
http://dx.doi.org/10.1093/protein/gzw037

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