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Proteomics to study DNA-bound and chromatin-associated gene regulatory complexes

High-resolution mass spectrometry (MS)-based proteomics is a powerful method for the identification of soluble protein complexes and large-scale affinity purification screens can decode entire protein interaction networks. In contrast, protein complexes residing on chromatin have been much more chal...

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Detalles Bibliográficos
Autores principales: Wierer, Michael, Mann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036873/
https://www.ncbi.nlm.nih.gov/pubmed/27402878
http://dx.doi.org/10.1093/hmg/ddw208