Effects of protein transduction domain (PTD) selection and position for improved intracellular delivery of PTD-Hsp27 fusion protein formulations

Protein drugs have attracted considerable attention as therapeutic agents due to their diversity and biocompatibility. However, hydrophilic proteins possess difficulty in penetrating lipophilic cell membrane. Although protein transduction domains (PTDs) have shown effectiveness in protein delivery,...

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Detalles Bibliográficos
Autores principales: Ul Ain, Qurrat, Lee, Jong Hwan, Woo, Young Sun, Kim, Yong-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pharmaceutical Society of Korea 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037156/
https://www.ncbi.nlm.nih.gov/pubmed/27381220
http://dx.doi.org/10.1007/s12272-016-0786-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037156/
https://www.ncbi.nlm.nih.gov/pubmed/27381220
http://dx.doi.org/10.1007/s12272-016-0786-9

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