Loss of ncm(5) and mcm(5) wobble uridine side chains results in an altered metabolic profile

INTRODUCTION: The Elongator complex, comprising six subunits (Elp1p-Elp6p), is required for formation of 5-carbamoylmethyl (ncm(5)) and 5-methoxycarbonylmethyl (mcm(5)) side chains on wobble uridines in 11 out of 42 tRNA species in Saccharomyces cerevisiae. Loss of these side chains reduces the effi...

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Detalles Bibliográficos
Autores principales: Karlsborn, Tony, Mahmud, A. K. M. Firoj, Tükenmez, Hasan, Byström, Anders S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037161/
https://www.ncbi.nlm.nih.gov/pubmed/27738410
http://dx.doi.org/10.1007/s11306-016-1120-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037161/
https://www.ncbi.nlm.nih.gov/pubmed/27738410
http://dx.doi.org/10.1007/s11306-016-1120-8

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