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In vivo Differential Brain Clearance and Catabolism of Monomeric and Oligomeric Alzheimer's Aβ protein

Amyloid β (Aβ) is the major constituent of the brain deposits found in parenchymal plaques and cerebral blood vessels of patients with Alzheimer's disease (AD). Several lines of investigation support the notion that synaptic pathology, one of the strongest correlates to cognitive impairment, is...

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Detalles Bibliográficos
Autores principales: McIntee, Farron L., Giannoni, Patrizia, Blais, Steven, Sommer, George, Neubert, Thomas A., Rostagno, Agueda, Ghiso, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037193/
https://www.ncbi.nlm.nih.gov/pubmed/27729857
http://dx.doi.org/10.3389/fnagi.2016.00223