Cargando…
In vivo Differential Brain Clearance and Catabolism of Monomeric and Oligomeric Alzheimer's Aβ protein
Amyloid β (Aβ) is the major constituent of the brain deposits found in parenchymal plaques and cerebral blood vessels of patients with Alzheimer's disease (AD). Several lines of investigation support the notion that synaptic pathology, one of the strongest correlates to cognitive impairment, is...
Autores principales: | McIntee, Farron L., Giannoni, Patrizia, Blais, Steven, Sommer, George, Neubert, Thomas A., Rostagno, Agueda, Ghiso, Jorge |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037193/ https://www.ncbi.nlm.nih.gov/pubmed/27729857 http://dx.doi.org/10.3389/fnagi.2016.00223 |
Ejemplares similares
-
N-terminally truncated Aβ4-x proteoforms and their relevance for Alzheimer’s pathophysiology
por: Rostagno, Agueda, et al.
Publicado: (2022) -
TRAIL death receptors DR4 and DR5 mediate cerebral microvascular endothelial cell apoptosis induced by oligomeric Alzheimer's Aβ
por: Fossati, S, et al.
Publicado: (2012) -
Correction to: Nrf2 activation through the PI3K/GSK-3 axisprotects neuronal cells from Aβ-mediatedoxidative and metabolic damage
por: Sotolongo, Krystal, et al.
Publicado: (2020) -
Nrf2 activation through the PI3K/GSK-3 axis protects neuronal cells from Aβ-mediated oxidative and metabolic damage
por: Sotolongo, Krystal, et al.
Publicado: (2020) -
Alzheimer’s amyloid β heterogeneous species differentially affect brain endothelial cell viability, blood‐brain barrier integrity, and angiogenesis
por: Parodi‐Rullán, Rebecca, et al.
Publicado: (2020)