ASPL-TFE3 Oncoprotein Regulates Cell Cycle Progression and Induces Cellular Senescence by Up-Regulating p21

Alveolar soft part sarcoma is an extremely rare soft tissue sarcoma with poor prognosis. It is characterized by the unbalanced recurrent chromosomal translocation der(17)t(X;17)(p11;q25), resulting in the generation of an ASPL-TFE3 fusion gene. ASPL-TFE3 oncoprotein functions as an aberrant transcri...

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Detalles Bibliográficos
Autores principales: Ishiguro, Naoko, Yoshida, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037204/
https://www.ncbi.nlm.nih.gov/pubmed/27673450
http://dx.doi.org/10.1016/j.neo.2016.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037204/
https://www.ncbi.nlm.nih.gov/pubmed/27673450
http://dx.doi.org/10.1016/j.neo.2016.08.001

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