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The Autonomic Nervous System Regulates the Heart Rate through cAMP-PKA Dependent and Independent Coupled-Clock Pacemaker Cell Mechanisms

Sinoatrial nodal cells (SANCs) generate spontaneous action potentials (APs) that control the cardiac rate. The brain modulates SANC automaticity, via the autonomic nervous system, by stimulating membrane receptors that activate (adrenergic) or inactivate (cholinergic) adenylyl cyclase (AC). However,...

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Detalles Bibliográficos
Autores principales: Behar, Joachim, Ganesan, Ambhighainath, Zhang, Jin, Yaniv, Yael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037226/
https://www.ncbi.nlm.nih.gov/pubmed/27729868
http://dx.doi.org/10.3389/fphys.2016.00419