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In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution

Essential elements as copper and iron modulate a wide range of physiological functions. Their metabolism is strictly regulated by cellular pathways, since dysregulation of metal homeostasis is responsible for many detrimental effects. Neurodegenerative disorders such as Alzheimer's disease, Par...

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Detalles Bibliográficos
Autores principales: Gasperini, Lisa, Meneghetti, Elisa, Legname, Giuseppe, Benetti, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037227/
https://www.ncbi.nlm.nih.gov/pubmed/27729845
http://dx.doi.org/10.3389/fnins.2016.00437