Cargando…
In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution
Essential elements as copper and iron modulate a wide range of physiological functions. Their metabolism is strictly regulated by cellular pathways, since dysregulation of metal homeostasis is responsible for many detrimental effects. Neurodegenerative disorders such as Alzheimer's disease, Par...
Autores principales: | Gasperini, Lisa, Meneghetti, Elisa, Legname, Giuseppe, Benetti, Federico |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037227/ https://www.ncbi.nlm.nih.gov/pubmed/27729845 http://dx.doi.org/10.3389/fnins.2016.00437 |
Ejemplares similares
-
Prion Protein and Copper Cooperatively Protect Neurons by Modulating NMDA Receptor Through S-nitrosylation
por: Gasperini, Lisa, et al.
Publicado: (2015) -
Copper coordination modulates prion conversion and infectivity in mammalian prion proteins
por: Legname, Giuseppe
Publicado: (2023) -
Structural Consequences of Copper Binding to the Prion Protein
por: Salzano, Giulia, et al.
Publicado: (2019) -
The non-octarepeat copper binding site of the prion protein is a key regulator of prion
conversion
por: Giachin, Gabriele, et al.
Publicado: (2015) -
De novo prions
por: Benetti, Federico, et al.
Publicado: (2010)