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Autocrine IL-10 functions as a rheostat for M1 macrophage glycolytic commitment by tuning nitric oxide production()()

Inflammatory maturation of M1 macrophages by proinflammatory stimuli such as toll like receptor ligands results in profound metabolic reprogramming resulting in commitment to aerobic glycolysis as evidenced by repression of mitochondrial oxidative phosphorylation (OXPHOS) and enhanced glucose utiliz...

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Detalles Bibliográficos
Autores principales: Baseler, Walter A., Davies, Luke C., Quigley, Laura, Ridnour, Lisa A., Weiss, Jonathan M., Hussain, S. Perwez, Wink, David A., McVicar, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037266/
https://www.ncbi.nlm.nih.gov/pubmed/27676159
http://dx.doi.org/10.1016/j.redox.2016.09.005