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Significant loss of sensitivity and specificity in the taxonomic classification occurs when short 16S rRNA gene sequences are used

The classification performance of Kraken was evaluated in terms of sensitivity and specificity when using short and long 16S rRNA sequences. A total of 440,738 sequences from bacteria with complete taxonomic classifications were downloaded from the high quality ribosomal RNA database SILVA. Amplicon...

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Detalles Bibliográficos
Autores principales: Martínez-Porchas, Marcel, Villalpando-Canchola, Enrique, Vargas-Albores, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037269/
https://www.ncbi.nlm.nih.gov/pubmed/27699286
http://dx.doi.org/10.1016/j.heliyon.2016.e00170