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Neddylation is required for herpes simplex virus type I (HSV-1)-induced early phase interferon-beta production

Type I interferons such as interferon-beta (IFN-β) play essential roles in the host innate immune response to herpes simplex virus type I (HSV-1) infection. The transcription of type I interferon genes is controlled by nuclear factor-κB (NF-κB) and interferon regulatory factor (IRF) family members i...

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Detalles Bibliográficos
Autores principales: Zhang, Xueying, Ye, Zhenjie, Pei, Yujun, Qiu, Guihua, Wang, Qingyang, Xu, Yunlu, Shen, Beifen, Zhang, Jiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037273/
https://www.ncbi.nlm.nih.gov/pubmed/27593482
http://dx.doi.org/10.1038/cmi.2015.35