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Neddylation is required for herpes simplex virus type I (HSV-1)-induced early phase interferon-beta production
Type I interferons such as interferon-beta (IFN-β) play essential roles in the host innate immune response to herpes simplex virus type I (HSV-1) infection. The transcription of type I interferon genes is controlled by nuclear factor-κB (NF-κB) and interferon regulatory factor (IRF) family members i...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037273/ https://www.ncbi.nlm.nih.gov/pubmed/27593482 http://dx.doi.org/10.1038/cmi.2015.35 |