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Suppressed expression of miR-378 targeting gzmb in NK cells is required to control dengue virus infection

Dengue virus (DENV) remains a major public health threat because no vaccine or drugs are available for the prevention and treatment of DENV infection, and the immunopathogenesis mechanisms of DENV infection are not fully understood. Cytotoxic molecules, such as granzyme B (GrzB), may be necessary to...

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Detalles Bibliográficos
Autores principales: Liu, Shuyan, Chen, Lingming, Zeng, Ying, Si, Lulu, Guo, Xiaolan, Zhou, Junmei, Fang, Danyun, Zeng, Gucheng, Jiang, Lifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037283/
https://www.ncbi.nlm.nih.gov/pubmed/26166761
http://dx.doi.org/10.1038/cmi.2015.52