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Suppressed expression of miR-378 targeting gzmb in NK cells is required to control dengue virus infection
Dengue virus (DENV) remains a major public health threat because no vaccine or drugs are available for the prevention and treatment of DENV infection, and the immunopathogenesis mechanisms of DENV infection are not fully understood. Cytotoxic molecules, such as granzyme B (GrzB), may be necessary to...
Autores principales: | Liu, Shuyan, Chen, Lingming, Zeng, Ying, Si, Lulu, Guo, Xiaolan, Zhou, Junmei, Fang, Danyun, Zeng, Gucheng, Jiang, Lifang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037283/ https://www.ncbi.nlm.nih.gov/pubmed/26166761 http://dx.doi.org/10.1038/cmi.2015.52 |
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