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Experimental factors affecting the robustness of DNA methylation analysis

Diverging methylation frequencies are often reported for the same locus in the same disease, underscoring the need for limiting technical variability in DNA methylation analyses. We have investigated seven likely sources of variability at different steps of bisulfite PCR-based DNA methylation analys...

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Detalles Bibliográficos
Autores principales: Pharo, Heidi D., Honne, Hilde, Vedeld, Hege M., Dahl, Christina, Andresen, Kim, Liestøl, Knut, Jeanmougin, Marine, Guldberg, Per, Lind, Guro E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037394/
https://www.ncbi.nlm.nih.gov/pubmed/27671843
http://dx.doi.org/10.1038/srep33936