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Experimental factors affecting the robustness of DNA methylation analysis
Diverging methylation frequencies are often reported for the same locus in the same disease, underscoring the need for limiting technical variability in DNA methylation analyses. We have investigated seven likely sources of variability at different steps of bisulfite PCR-based DNA methylation analys...
Autores principales: | Pharo, Heidi D., Honne, Hilde, Vedeld, Hege M., Dahl, Christina, Andresen, Kim, Liestøl, Knut, Jeanmougin, Marine, Guldberg, Per, Lind, Guro E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037394/ https://www.ncbi.nlm.nih.gov/pubmed/27671843 http://dx.doi.org/10.1038/srep33936 |
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