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Transition zone assembly and its contribution to axoneme formation in Drosophila male germ cells

The ciliary transition zone (TZ) is a complex structure found at the cilia base. Defects in TZ assembly are associated with human ciliopathies. In most eukaryotes, three protein complexes (CEP290, NPHP, and MKS) cooperate to build the TZ. We show that in Drosophila melanogaster, mild TZ defects are...

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Detalles Bibliográficos
Autores principales: Vieillard, Jennifer, Paschaki, Marie, Duteyrat, Jean-Luc, Augière, Céline, Cortier, Elisabeth, Lapart, Jean-André, Thomas, Joëlle, Durand, Bénédicte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037411/
https://www.ncbi.nlm.nih.gov/pubmed/27646273
http://dx.doi.org/10.1083/jcb.201603086