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The Dinoflagellate Toxin 20-Methyl Spirolide-G Potently Blocks Skeletal Muscle and Neuronal Nicotinic Acetylcholine Receptors

The cyclic imine toxin 20-methyl spirolide G (20-meSPX-G), produced by the toxigenic dinoflagellate Alexandrium ostenfeldii/Alexandrium peruvianum, has been previously reported to contaminate shellfish in various European coastal locations, as revealed by mouse toxicity bioassay. The aim of the pres...

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Detalles Bibliográficos
Autores principales: Couesnon, Aurélie, Aráoz, Rómulo, Iorga, Bogdan I., Benoit, Evelyne, Reynaud, Morgane, Servent, Denis, Molgó, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037475/
https://www.ncbi.nlm.nih.gov/pubmed/27563924
http://dx.doi.org/10.3390/toxins8090249