A Novel Zak Knockout Mouse with a Defective Ribotoxic Stress Response

Ricin activates the proinflammatory ribotoxic stress response through the mitogen activated protein 3 kinase (MAP3K) ZAK, resulting in activation of mitogen activated protein kinases (MAPKs) p38 and JNK1/2. We had a novel zak−/− mouse generated to study the role of ZAK signaling in vivo during ricin...

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Detalles Bibliográficos
Autores principales: Jandhyala, Dakshina M., Wong, John, Mantis, Nicholas J., Magun, Bruce E., Leong, John M., Thorpe, Cheleste M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037485/
https://www.ncbi.nlm.nih.gov/pubmed/27598200
http://dx.doi.org/10.3390/toxins8090259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037485/
https://www.ncbi.nlm.nih.gov/pubmed/27598200
http://dx.doi.org/10.3390/toxins8090259

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