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Effects of Folic Acid on Secretases Involved in Aβ Deposition in APP/PS1 Mice

Alzheimer’s disease (AD) is the most common type of dementia. Amyloid-β protein (Aβ) is identified as the core protein of neuritic plaques. Aβ is generated by the sequential cleavage of the amyloid precursor protein (APP) via the APP cleaving enzyme (α-secretase, or β-secretase) and γ-secretase. Pre...

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Detalles Bibliográficos
Autores principales: Tian, Tian, Bai, Dong, Li, Wen, Huang, Guo-Wei, Liu, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037541/
https://www.ncbi.nlm.nih.gov/pubmed/27618097
http://dx.doi.org/10.3390/nu8090556