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Effects of Folic Acid on Secretases Involved in Aβ Deposition in APP/PS1 Mice
Alzheimer’s disease (AD) is the most common type of dementia. Amyloid-β protein (Aβ) is identified as the core protein of neuritic plaques. Aβ is generated by the sequential cleavage of the amyloid precursor protein (APP) via the APP cleaving enzyme (α-secretase, or β-secretase) and γ-secretase. Pre...
Autores principales: | Tian, Tian, Bai, Dong, Li, Wen, Huang, Guo-Wei, Liu, Huan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037541/ https://www.ncbi.nlm.nih.gov/pubmed/27618097 http://dx.doi.org/10.3390/nu8090556 |
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