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Anti-cancer activity of Psoralea fructus through the downregulation of cyclin D1 and CDK4 in human colorectal cancer cells

BACKGROUND: Psoralea Fructus (PF), the dried and ripe fruit of Psoralea corylifolia exhibits an anti-cancer activity. However, the molecular mechanisms by which PF inhibits the proliferation of cancer cells have not been elucidated in detail. Cyclin D1 and CDK4 are important regulatory proteins in c...

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Detalles Bibliográficos
Autores principales: Park, Gwang Hun, Sung, Ji Ho, Song, Hun Min, Jeong, Jin Boo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037586/
https://www.ncbi.nlm.nih.gov/pubmed/27670681
http://dx.doi.org/10.1186/s12906-016-1364-x