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Autologous bone grafts with MSCs or FGF-2 accelerate bone union in large bone defects

BACGROUND: Although the contribution of fibroblast growth factor (FGF)-2 and mesenchymal stromal cells (MSCs) to bone formation is well known, few studies have investigated the combination of an autologous bone graft with FGF-2 or MSCs for large bone defects. METHODS: We studied an atrophic non-unio...

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Detalles Bibliográficos
Autores principales: Murakami, Hiroaki, Nakasa, Tomoyuki, Ishikawa, Masakazu, Adachi, Nobuo, Ochi, Mitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037630/
https://www.ncbi.nlm.nih.gov/pubmed/27669690
http://dx.doi.org/10.1186/s13018-016-0442-6