Silencing of CD47 and SIRPα by Polypurine reverse Hoogsteen hairpins to promote MCF-7 breast cancer cells death by PMA-differentiated THP-1 cells

BACKGROUND: In the context of tumor immunology, tumor cells have been shown to overexpress CD47, an anti-phagocytic signal directed to macrophages to escape from phagocytosis by interacting with Signal Regulatory Protein α SIRPα. In the present work, we designed Polypurine reverse Hoogsteen hairpins...

Descripción completa

Detalles Bibliográficos
Autores principales: Bener, Gizem, J. Félix, Alex, Sánchez de Diego, Cristina, Pascual Fabregat, Isabel, Ciudad, Carlos J., Noé, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037635/
https://www.ncbi.nlm.nih.gov/pubmed/27671753
http://dx.doi.org/10.1186/s12865-016-0170-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037635/
https://www.ncbi.nlm.nih.gov/pubmed/27671753
http://dx.doi.org/10.1186/s12865-016-0170-z

Ejemplares similares