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Kinase Signaling in Apoptosis Induced by Saturated Fatty Acids in Pancreatic β-Cells

Pancreatic β-cell failure and death is considered to be one of the main factors responsible for type 2 diabetes. It is caused by, in addition to hyperglycemia, chronic exposure to increased concentrations of fatty acids, mainly saturated fatty acids. Molecular mechanisms of apoptosis induction by sa...

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Detalles Bibliográficos
Autores principales: Šrámek, Jan, Němcová-Fürstová, Vlasta, Kovář, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037680/
https://www.ncbi.nlm.nih.gov/pubmed/27626409
http://dx.doi.org/10.3390/ijms17091400