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Kinase Signaling in Apoptosis Induced by Saturated Fatty Acids in Pancreatic β-Cells
Pancreatic β-cell failure and death is considered to be one of the main factors responsible for type 2 diabetes. It is caused by, in addition to hyperglycemia, chronic exposure to increased concentrations of fatty acids, mainly saturated fatty acids. Molecular mechanisms of apoptosis induction by sa...
Autores principales: | Šrámek, Jan, Němcová-Fürstová, Vlasta, Kovář, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037680/ https://www.ncbi.nlm.nih.gov/pubmed/27626409 http://dx.doi.org/10.3390/ijms17091400 |
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