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Detection of Natural Resistance-Associated Substitutions by Ion Semiconductor Technology in HCV1b Positive, Direct-Acting Antiviral Agents-Naïve Patients

Naturally occurring resistance-associated substitutions (RASs) can negatively impact the response to direct-acting antivirals (DAAs) agents-based therapies for hepatitis C virus (HCV) infection. Herein, we set out to characterize the RASs in the HCV1b genome from serum samples of DAA-naïve patients...

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Detalles Bibliográficos
Autores principales: Marascio, Nadia, Pavia, Grazia, Strazzulla, Alessio, Dierckx, Tim, Cuypers, Lize, Vrancken, Bram, Barreca, Giorgio Settimo, Mirante, Teresa, Malanga, Donatella, Oliveira, Duarte Mendes, Vandamme, Anne-Mieke, Torti, Carlo, Liberto, Maria Carla, Focà, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037695/
https://www.ncbi.nlm.nih.gov/pubmed/27618896
http://dx.doi.org/10.3390/ijms17091416