Ruscogenin Attenuates Cerebral Ischemia-Induced Blood-Brain Barrier Dysfunction by Suppressing TXNIP/NLRP3 Inflammasome Activation and the MAPK Pathway

Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, has been shown to inhibit cerebral ischemic injury. However, its potential molecular action on blood-brain barrier (BBB) dysfunction after stroke remains unclear. This study aimed to investigate the effects of ruscogenin o...

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Detalles Bibliográficos
Autores principales: Cao, Guosheng, Jiang, Nan, Hu, Yang, Zhang, Yuanyuan, Wang, Guangyun, Yin, Mingzhu, Ma, Xiaonan, Zhou, Kecheng, Qi, Jin, Yu, Boyang, Kou, Junping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037697/
https://www.ncbi.nlm.nih.gov/pubmed/27589720
http://dx.doi.org/10.3390/ijms17091418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037697/
https://www.ncbi.nlm.nih.gov/pubmed/27589720
http://dx.doi.org/10.3390/ijms17091418

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