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DNA Interaction Studies of Selected Polyamine Conjugates

The interaction of polyamine conjugates with DNA double helix has been studied. Binding properties were examined by ethidium bromide (EtBr) displacement and DNA unwinding/topoisomerase I/II (Topo I/II) activity assays, as well as dsDNA thermal stability studies and circular dichroism spectroscopy. G...

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Detalles Bibliográficos
Autores principales: Szumilak, Marta, Merecz, Anna, Strek, Malgorzata, Stanczak, Andrzej, Inglot, Tadeusz W., Karwowski, Boleslaw T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037830/
https://www.ncbi.nlm.nih.gov/pubmed/27657041
http://dx.doi.org/10.3390/ijms17091560