Cargando…

Changes in peripheral blood lymphocytes in polycythemia vera and essential thrombocythemia patients treated with pegylated-interferon alpha and correlation with JAK2(V617F) allelic burden

BACKGROUND: Pegylated-interferon alpha (PegINFα) treatment of patients with polycythemia vera (PV) and essential thrombocythemia (ET) has resulted in long-term clinical response, decreased JAK2 (V617F) allelic burden and restoration of polyclonal hematopoiesis. The mechanisms of the beneficial effec...

Descripción completa

Detalles Bibliográficos
Autores principales: Kovacsovics-Bankowski, Magdalena, Kelley, Todd W., Efimova, Olga, Kim, Soo Jin, Wilson, Andrew, Swierczek, Sabina, Prchal, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037882/
https://www.ncbi.nlm.nih.gov/pubmed/27708986
http://dx.doi.org/10.1186/s40164-016-0057-y