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Small cell lung cancer growth is inhibited by miR-342 through its effect of the target gene IA-2

BACKGROUND: Small cell lung cancers (SCLC) are tumors of neuroendocrine origin. Previous in vitro studies from our laboratory showed that SCLC expresses high levels of the transmembrane dense core vesicle protein IA-2 (islet cell antigen-2) as compared to normal lung cells. IA-2, through its effect...

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Detalles Bibliográficos
Autores principales: Xu, Huanyu, Cai, Tao, Carmona, Gilberto N., Abuhatzira, Liron, Notkins, Abner L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037891/
https://www.ncbi.nlm.nih.gov/pubmed/27670444
http://dx.doi.org/10.1186/s12967-016-1036-0