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Unexpected effects of the MIP‐Cre(ER) transgene and tamoxifen on β‐cell growth in C57Bl6/J male mice

Transgenic mouse models have been fundamental in the discovery of factors that regulate β‐cell development, mass, and function. Several groups have recently shown that some of these models display previously uncharacterized phenotypes due to the transgenic system itself. These include impaired islet...

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Detalles Bibliográficos
Autores principales: Carboneau, Bethany A., Le, Thao D. V., Dunn, Jennifer C., Gannon, Maureen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037909/
https://www.ncbi.nlm.nih.gov/pubmed/27670405
http://dx.doi.org/10.14814/phy2.12863